PUF60 anticorps

N° du produit ABIN2462252

Détail du produit anti-PUF60 anticorps

Antigène: PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PUF60 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PUF60.

Information d'application

Indications d'application: PUF60 antibody can be used for detection of PUF60 by ELISA at 1:312500. PUF60 antibody can be used for detection of PUF60 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PUF60 antibody at -20 °C.

Détails sur PUF60

Antigène: PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

Autre désignation: PUF60 (PUF60 Produits)

Synonymes: anticorps FIR, anticorps RoBPI, anticorps SIAHBP1, anticorps fc21a05, anticorps wu:fc21a05, anticorps wu:fi43a08, anticorps 2410104I19Rik, anticorps 2810454F19Rik, anticorps Siahbp1, anticorps fe37c05, anticorps repressor, anticorps si:ch211-12p8.2, anticorps si:zc12p8.2, anticorps wu:fb33e11, anticorps wu:fe37c05, anticorps zgc:86806, anticorps poly(U) binding splicing factor 60, anticorps poly-U binding splicing factor a, anticorps poly-U binding splicing factor 60, anticorps poly-U binding splicing factor b, anticorps PUF60, anticorps puf60a, anticorps Puf60, anticorps puf60b

Sujet: PUF60 is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription.The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.

Poids moléculaire: 58 kDa

ID gène: 22827

NCBI Accession: NP_055096