DCP2 anticorps

N° du produit ABIN2462345

Détail du produit anti-DCP2 anticorps

Antigène: DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCP2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DCP2.

Information d'application

Indications d'application: DCP2 antibody can be used for detection of DCP2 by ELISA at 1:62500. DCP2 antibody can be used for detection of DCP2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DCP2 antibody at -20 °C.

Détails sur DCP2

Antigène: DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))

Autre désignation: DCP2 (DCP2 Produits)

Synonymes: anticorps DDBDRAFT_0185453, anticorps DDBDRAFT_0252811, anticorps DDB_0185453, anticorps DDB_0252811, anticorps 2410015D23Rik, anticorps 5730537H01Rik, anticorps AL118268, anticorps NUDT20, anticorps RGD1562909, anticorps mRNA-decapping enzyme 2, anticorps hypothetical protein, anticorps decapping mRNA 2, anticorps CpipJ_CPIJ019463, anticorps PTRG_05936, anticorps dcp2, anticorps MCYG_05106, anticorps MGYG_07617, anticorps PGTG_03310, anticorps Tsp_04018, anticorps DCP2, anticorps Dcp2

Sujet: DCP2 is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. DCP2 removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. It has higher activity towards mRNAs that lack a poly (A) tail, but has no activity towards a cap structure lacking a RNA moiety.DCP2 is a key component of an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).

Poids moléculaire: 48 kDa

ID gène: 167227

NCBI Accession: NP_689837

UniProt: Q8IU60