GSTM2 anticorps

N° du produit ABIN2462480

Détail du produit anti-GSTM2 anticorps

Antigène: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTM2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GSTM2.

Information d'application

Indications d'application: GSTM2 antibody can be used for detection of GSTM2 by ELISA at 1:312500. GSTM2 antibody can be used for detection of GSTM2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GSTM2 antibody at -20 °C.

Détails sur GSTM2

Antigène: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Autre désignation: GSTM2 (GSTM2 Produits)

Synonymes: anticorps GSTA4, anticorps GST4, anticorps GSTM, anticorps GSTM2-2, anticorps GTHMUS, anticorps Gstb-2, anticorps Gstb2, anticorps GSTIV, anticorps glutathione S-transferase mu 2, anticorps glutathione S-transferase mu 2 (muscle), anticorps glutathione S-transferase Mu 2, anticorps glutathione S-transferase, mu 2, anticorps glutathione S-transferase 2, anticorps Glutathione S-transferase 4, anticorps Gstm2, anticorps GSTM2, anticorps LOC100732167, anticorps gst2, anticorps gst-4

Sujet: At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. GSTM2 is a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.

Poids moléculaire: 26 kDa

ID gène: 2946

NCBI Accession: NP_000839

UniProt: P28161

Pathways: Negative Regulation of Transporter Activity