P-Cadherin anticorps

N° du produit ABIN2462833

Détail du produit anti-P-Cadherin anticorps

Antigène: P-Cadherin (CDH3)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P-Cadherin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDH3.

Information d'application

Indications d'application: CDH3 antibody can be used for detection of CDH3 by ELISA at 1:1562500. CDH3 antibody can be used for detection of CDH3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CDH3 antibody at -20 °C.

Détails sur P-Cadherin

Antigène: P-Cadherin (CDH3)

Autre désignation: CDH3 (CDH3 Produits)

Synonymes: anticorps CDH3, anticorps Cadherin-3, anticorps AI385538, anticorps Cadp, anticorps Cdhp, anticorps P-cadherin, anticorps Pcad, anticorps CDHP, anticorps HJMD, anticorps PCAD, anticorps E-Cad, anticorps E-cadherin, anticorps EP-cadherin, anticorps XTCAD-1, anticorps c-cadherin, anticorps cadherin-1, anticorps cdh1, anticorps cdh1-b, anticorps cdh3, anticorps cdhc-A, anticorps cdhp, anticorps hjmd, anticorps l-cam, anticorps lcam, anticorps pcad, anticorps uvo, anticorps uvomorulin, anticorps xb-cad, anticorps xcdh1, anticorps CDH15, anticorps K-CAM, anticorps cadherin 3, anticorps cadherin 3 L homeolog, anticorps Cadherin-3, anticorps CDH3, anticorps Cdh3, anticorps cdh3.L, anticorps cdh-3

Sujet: CDH3 is a classical cadherin from the cadherin superfamily. The protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Its gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in its gene have been associated with congential hypotrichosis with juvenile macular dystrophy.This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.

Poids moléculaire: 91 kDa

ID gène: 1001

NCBI Accession: NP_001784

UniProt: P22223