PTPRN antibody can be used for detection of PTPRN by ELISA at 1:12500. PTPRN antibody can be used for detection of PTPRN by western blot at 0.0625 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Concentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Conseil sur la manipulation
As with any antibody avoid repeat freeze-thaw cycles.
Stock
4 °C/-20 °C
Stockage commentaire
For short periods of storage (days) store at 4 °C. For longer periods of storage, store PTPRN antibody at -20 °C.
Antigène
PTPRN
(Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
anticorps IA-2, anticorps IA-2/PTP, anticorps IA2, anticorps ICA512, anticorps R-PTP-N, anticorps mIA-A, anticorps mKIAA4064, anticorps Ia-2, anticorps fc43c04, anticorps ptprn, anticorps wu:fc43c04, anticorps ia-2, anticorps ia2, anticorps ica512, anticorps r-ptp-n, anticorps protein tyrosine phosphatase, receptor type N, anticorps protein tyrosine phosphatase, receptor type, N, anticorps protein tyrosine phosphatase, receptor type, Na, anticorps protein tyrosine phosphatase, receptor type N L homeolog, anticorps PTPRN, anticorps Ptprn, anticorps ptprna, anticorps ptprn.L
Sujet
PTPRN is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus.