PTPRN anticorps (Middle Region)

N° du produit ABIN2782197

Détail du produit anti-PTPRN anticorps

Antigène: PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Porc, Cobaye, Lapin, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPRN est non-conjugé

Application: Western Blotting (WB)

Séquence: EVQQVPSPVS SEPPKAARPP VTPVLLEKKS PLGQSQPTVA GQPSARPAAE

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PTPRN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PTPRN

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 591 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PTPRN

Antigène: PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))

Autre désignation: PTPRN (PTPRN Produits)

Synonymes: anticorps IA-2, anticorps IA-2/PTP, anticorps IA2, anticorps ICA512, anticorps R-PTP-N, anticorps mIA-A, anticorps mKIAA4064, anticorps Ia-2, anticorps fc43c04, anticorps ptprn, anticorps wu:fc43c04, anticorps ia-2, anticorps ia2, anticorps ica512, anticorps r-ptp-n, anticorps protein tyrosine phosphatase, receptor type N, anticorps protein tyrosine phosphatase, receptor type, N, anticorps protein tyrosine phosphatase, receptor type, Na, anticorps protein tyrosine phosphatase, receptor type N L homeolog, anticorps PTPRN, anticorps Ptprn, anticorps ptprna, anticorps ptprn.L

Sujet: PTPRN is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus.
Alias Symbols: FLJ16131, IA-2, IA-2/PTP, IA2, ICA512, R-PTP-N
Protein Interaction Partner: PLP1, MAL, CLN8, UBQLN4, SNX19, SPTBN4, PTPRT, MADD, PTPRS, SNTB2, NOS1, PPIA, CAPN2,
Protein Size: 889

Poids moléculaire: 96 kDa

ID gène: 5798

NCBI Accession: NM_001199763

UniProt: Q16849