Arrestin 3 anticorps
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- Antigène Voir toutes Arrestin 3 (ARRB2) Anticorps
- Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
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Reactivité
- Humain, Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Arrestin 3 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogène
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ARRB2.
- Top Product
- Discover our top product ARRB2 Anticorps primaire
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- Indications d'application
- ARRB2 antibody can be used for detection of ARRB2 by ELISA at 1:312500. ARRB2 antibody can be used for detection of ARRB2 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Conseil sur la manipulation
- As with any antibody avoid repeat freeze-thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store ARRB2 antibody at -20 °C.
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- Antigène
- Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
- Autre désignation
- ARRB2 (ARRB2 Produits)
- Synonymes
- anticorps ARRB2, anticorps arb2, anticorps arr2, anticorps arrestin, anticorps barr2, anticorps betaarr2, anticorps ARB2, anticorps ARR2, anticorps BARR2, anticorps BARRES, anticorps AI326910, anticorps AW122872, anticorps arrb2, anticorps zgc:64007, anticorps arrestin beta 2, anticorps arrestin, beta 2, anticorps arrestin beta 2 L homeolog, anticorps arrestin, beta 2b, anticorps ARRB2, anticorps arrb2, anticorps Arrb2, anticorps arrb2.L, anticorps arrb2b
- Sujet
- Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. ARRB2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors.Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
- Poids moléculaire
- 44 kDa, 46 kDa
- ID gène
- 409
- NCBI Accession
- NP_945355
- UniProt
- A8K4I6
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling
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