POLR2H anticorps

N° du produit ABIN2463203

Détail du produit anti-POLR2H anticorps

Antigène: POLR2H (Polymerase (RNA) II (DNA Directed) Polypeptide H (POLR2H))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLR2H est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human POLR2H.

Information d'application

Indications d'application: POLR2H antibody can be used for detection of POLR2H by ELISA at 1:500. POLR2H antibody can be used for detection of POLR2H by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store POLR2H antibody at -20 °C.

Détails sur POLR2H

Antigène: POLR2H (Polymerase (RNA) II (DNA Directed) Polypeptide H (POLR2H))

Autre désignation: POLR2H (POLR2H Produits)

Synonymes: anticorps RPABC3, anticorps RPB17, anticorps RPB8, anticorps POLR2H, anticorps RGD1561203, anticorps rpb8, anticorps rpb17, anticorps hsrpb8, anticorps rpabc3, anticorps zgc:110289, anticorps RNA polymerase II subunit H, anticorps polymerase (RNA) II (DNA directed) polypeptide H, anticorps polymerase (RNA) II subunit H L homeolog, anticorps polymerase (RNA) II subunit H, anticorps info polymerase (RNA) II (DNA directed) polypeptide H, anticorps POLR2H, anticorps Polr2h, anticorps polr2h.L, anticorps polr2h

Sujet: POLR2H is one of the essential subunits of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III.This gene encodes one of the essential subunits of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. This gene encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. Multiple transcript variants have been reported for this gene, but it has not been clearly demonstrated that they encode valid isoforms. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-400 AU142999.1 1-400 401-907 BI772069.1 287-793 908-1792 BC008348.1 928-1812 1793-3185 AC099344.4 111461-112853 c

Poids moléculaire: 17 kDa

ID gène: 5437

NCBI Accession: NP_006223

UniProt: P52434

Pathways: Regulatory RNA Pathways