PAXIP1 anticorps
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- Antigène Voir toutes PAXIP1 Anticorps
- PAXIP1 (PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PAXIP1 est non-conjugé
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Application
- ELISA, Western Blotting (WB)
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogène
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PAXIP1.
- Top Product
- Discover our top product PAXIP1 Anticorps primaire
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- Indications d'application
- PAXIP1 antibody can be used for detection of PAXIP1 by ELISA at 1:62500. PAXIP1 antibody can be used for detection of PAXIP1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Conseil sur la manipulation
- As with any antibody avoid repeat freeze-thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store PAXIP1 antibody at -20 °C.
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- Antigène
- PAXIP1 (PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1))
- Autre désignation
- PAXIP1 (PAXIP1 Produits)
- Synonymes
- anticorps CAGF29, anticorps PACIP1, anticorps PAXIP1L, anticorps PTIP, anticorps TNRC2, anticorps wu:fa04b06, anticorps zgc:92593, anticorps cagf28, anticorps cagf29, anticorps k14, anticorps pacip1, anticorps paxip1l, anticorps ptip, anticorps tnrc2, anticorps D5Ertd149e, anticorps PAX interacting protein 1, anticorps PAX interacting (with transcription-activation domain) protein 1, anticorps PAX interacting protein 1 L homeolog, anticorps PAXIP1, anticorps paxip1, anticorps paxip1.L, anticorps Paxip1
- Sujet
- PAXIP1 functions as a key component of the DNA damage response, and phosphoserine or phosphothreonine-specific binding modules. PAXIP1 recognizes substrates phosphorylated by the kinases ataxia telangiectasia-mutated (ATM), ataxia telangiectasia and RAD3-related (ATR) in response to gamma irradiation. It may play a role in PAX2-dependent transcriptional regulation. PAXIP1 plays a role in early development, most probably in cell proliferation.
- Poids moléculaire
- 74 kDa
- ID gène
- 22976
- UniProt
- Q6ZW49
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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