DNAJC24 anticorps

N° du produit ABIN2463559

Détail du produit anti-DNAJC24 anticorps

Antigène: DNAJC24 (DnaJ (Hsp40) Homolog, Subfamily C, Member 24 (DNAJC24))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNAJC24 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DPH4.

Information d'application

Indications d'application: DPH4 antibody can be used for detection of DPH4 by ELISA at 1:312500. DPH4 antibody can be used for detection of DPH4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DPH4 antibody at -20 °C.

Détails sur DNAJC24

Antigène: DNAJC24 (DnaJ (Hsp40) Homolog, Subfamily C, Member 24 (DNAJC24))

Autre désignation: DPH4 (DNAJC24 Produits)

Synonymes: anticorps DPH4, anticorps JJJ3, anticorps ZCSL3, anticorps 1700030A21Rik, anticorps 2610027M02Rik, anticorps AV066965, anticorps AW240712, anticorps Dph4, anticorps MmDjC7, anticorps Zcsl3, anticorps RGD1564710, anticorps DnaJ heat shock protein family (Hsp40) member C24, anticorps DNAJC24, anticorps Dnajc24

Sujet: Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2.Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).

Poids moléculaire: 17 kDa

ID gène: 120526

NCBI Accession: NP_859057

UniProt: Q6P3W2