Endoglin anticorps (AA 341-470)
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- Antigène Voir toutes Endoglin (ENG) Anticorps
- Endoglin (ENG)
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Épitope
- AA 341-470
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Reactivité
- Humain
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Hôte
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Poulet
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Endoglin est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Immunoaffinity Purified
- Top Product
- Discover our top product ENG Anticorps primaire
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- Indications d'application
- Endoglin antibody can be used for the detection of Endoglin by Western Blot.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Phosphate-Buffered Saline. No preservatives added.
- Agent conservateur
- Without preservative
- Conseil sur la manipulation
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- ENG antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
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- Antigène
- Endoglin (ENG)
- Autre désignation
- ENG (ENG Produits)
- Synonymes
- anticorps ENG, anticorps MGC137842, anticorps DKFZp469D0419, anticorps END, anticorps HHT1, anticorps ORW1, anticorps AI528660, anticorps AI662476, anticorps CD105, anticorps S-endoglin, anticorps endoglin, anticorps ENG, anticorps Eng
- Sujet
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FUNCTION: Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.
DISEASE: Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300], also known as Rendu-Osler-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations, all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity. - Poids moléculaire
- 70.6 kDa (calculated)
- ID gène
- 2022
- NCBI Accession
- NP_000109
- UniProt
- P17813
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