NR5A1
Reactivité: Humain, Souris, Rat
WB, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Steroidogenic Factor 1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, 0.1 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
As with all antibodies avoid freeze/thaw cycles.
Stock
4 °C/-80 °C
Stockage commentaire
Steroidogenic Factor 1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
Antigène
NR5A1
(Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1))
anticorps AD4BP, anticorps ELP, anticorps FTZ1, anticorps FTZF1, anticorps POF7, anticorps SF-1, anticorps SF1, anticorps SPGF8, anticorps SRXY3, anticorps Ad4BP, anticorps ELP-3, anticorps Ftz-F1, anticorps Ftzf1, anticorps Ad4BP/SF-1, anticorps Ad4bp, anticorps Sf-1, anticorps NR5A1, anticorps sf-1, anticorps elp, anticorps sf1, anticorps ftz1, anticorps ad4bp, anticorps ftzf1, anticorps SF-1/Ad4BP, anticorps SI:zC167P9.2, anticorps ff1d, anticorps nr5a2l, anticorps nuclear receptor subfamily 5 group A member 1, anticorps nuclear receptor subfamily 5, group A, member 1, anticorps nuclear receptor subfamily 5 group A member 1 L homeolog, anticorps nuclear receptor subfamily 6 group A member 1, anticorps nuclear receptor subfamily 5, group A, member 1b, anticorps NR5A1, anticorps Nr5a1, anticorps nr5a1.L, anticorps nr5a1, anticorps NR6A1, anticorps nr5a1b
Sujet
Steroidogenic factor 1 (SF-1), a NR5 Fushi Tarazu-Like Receptor, has been shown to affect sexual differentiation, steroid metabolism, and neural development. SF-1 binds as a monomer and regulates all steroidogenic p450 genes, Mullerian inhibiting substance, the gonadotrophins, the ACTH receptor, oxytocin, nuclear receptor DAX-1, and several other genes. Four alternatively spliced isoforms of SF-1 have been isolated in mice, and they differ at the N and C termini but are identical in the DNA-binding domain.