RAMP3 antibody can be used in ELISA starting at 1:3000 - 1:6000, Western Blot starting at 1:3000 - 1:6000, immunohistochemistry starting at 10 μg/mL, and immunoprecipitation
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, 0.01 % sodium azide, 50 % glycerol.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
As with all antibodies avoid freeze/thaw cycles.
Stock
4 °C/-20 °C
Stockage commentaire
Store RAMP3 antibody at 4 °C or -20 °C.
Antigène
RAMP3
(Receptor (G Protein-Coupled) Activity Modifying Protein 3 (RAMP3))
anticorps RAMP3, anticorps ramp3, anticorps AI850306, anticorps receptor activity modifying protein 3, anticorps receptor (G protein-coupled) activity modifying protein 3, anticorps Receptor activity-modifying protein 3, anticorps receptor (calcitonin) activity modifying protein 3, anticorps RAMP3, anticorps ramp3, anticorps Ramp3
Sujet
RAMP3 is a member of the RAMP family of single-transmembrane-domain proteins, called receptor-activity-modifying proteins. RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. Co-expression of RAMP3 with CRLR results in the production of a functional adrenomedullin receptor.