SPRY4 anticorps (AA 306-322)

N° du produit ABIN2470367

Détail du produit anti-SPRY4 anticorps

Antigène: SPRY4 (Sprouty RTK Signaling Antagonist 4 (SPRY4))

Épitope: AA 306-322

Reactivité: Humain, Chimpanzé

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPRY4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Immunoaffinity Chromatography

Immunogène: SPRY4 antibody was raised against amino acids 306-322 of SPRY4 (Human).

Information d'application

Indications d'application: SPRY4 antibody can be used in Western Blot, immunohistochemistry starting at 1:200, and immunoprecipitation.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies avoid freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store SPRY4 antibody at 4 °C or -20 °C.

Détails sur SPRY4

Antigène: SPRY4 (Sprouty RTK Signaling Antagonist 4 (SPRY4))

Autre désignation: SPRY4 (SPRY4 Produits)

Synonymes: anticorps SPRY4, anticorps LOC100218545, anticorps HH17, anticorps A030006O18Rik, anticorps sprouty4, anticorps sprouty RTK signaling antagonist 4, anticorps sprouty (Drosophila) homolog 4, anticorps sprouty homolog 4 (Drosophila), anticorps Spry4, anticorps SPRY4, anticorps spry4

Sujet: Sprouty-4 (also known as SPRY4) is an inhibitor of the insulin receptor and EGFR-transduced mitogen-activated protein kinase (MAPK) signaling pathway downstream of FGF and EGF receptor tyrosine kinase activation. It is positioned upstream of RAS activation and impairs the formation of active GTP-RAS. SPRY4 is widely expressed, with different isoforms. The protein consists of 322 amino acids, with a cysteine-rich region, Src homology 3 binding regions, proline-rich regions, and a PEST sequence. It is expressed predominantly in the cytoplasm. Northern results show bands across most tissues, with strongest expression in heart, brain, placenta, lung, and intestine.

ID gène: 81848

UniProt: Q9C004