CDKN1A anticorps (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1))

Details for Product anti-CDKN1A Antibody No. ABIN2475991
Antigène
Reactivité
Humain
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39
7
6
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4
1
1
1
1
1
1
1
Hôte
Souris
339
179
1
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp CDKN1A est non-conjugé
31
22
22
15
15
15
9
9
9
9
9
9
5
5
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5
5
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Application
Immunoprecipitation (IP), Western Blotting (WB)
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53
27
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Options
Immunogène Human p21 protein
Clone WA-1
Isotype IgG1
Specificité This antibody recognises the human cyclin-dependent kinase inhibitor p21/WAF1, which is an important cell cycle regulatory protein, also known as CIP1.The p21 protein inhibits cell cycle progression at both the G1 and G2 checkpoints. The expression of p21 is inducible by a wide range of stress stimuli.This antibody detects a band of approximately 21kD in MCF-7 cell lysates following UV radiation.
Attributs du produit Purified IgG
Purification Purified
Antigène
Autre désignation p21/WAF1 (CDKN1A Antibody Extrait)
ID gène 1026
UniProt P38936
Pathways Signalisation p53, Signalisation PI3K-Akt, Cycle Cellulaire, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Hepatitis C, Synthesis of DNA, Autophagy
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Images (Fournisseur)
Image no. 1 for anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) antibody (ABIN2475991) anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) antibody
Produit citée dans: Kotala, Uldrijan, Horky, Trbusek, Strnad, Vojtesek: "Potent induction of wild-type p53-dependent transcription in tumour cells by a synthetic inhibitor of cyclin-dependent kinases." dans: Cellular and molecular life sciences : CMLS, Vol. 58, Issue 9, pp. 1333-9, 2001 (PubMed).

Kolár, Murray, Scott, Harrison, Vojt?sek, Dusek: "Relation of Bcl-2 expression to androgen receptor, p21WAF1/CIP1, and cyclin D1 status in prostate cancer." dans: Molecular pathology : MP, Vol. 53, Issue 1, pp. 15-8, 2000 (PubMed).