TRAP1 anticorps

N° du produit ABIN2484668

Détail du produit anti-TRAP1 anticorps

Antigène: TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TRAP1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: Detects ~75 kDa.

Réactivité croisée: Humain, Souris, Rat

Purification: Protein G Purified

Immunogène: Purified recombinant TRAP1

Clone: 3H4-2H6

Isotype: IgG1 kappa

Information d'application

Indications d'application:

• WB (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Commentaires:

1 μg/ml of ABIN2484668 was sufficient for detection of Trap-1/HSP75 in 20 μg of Human A431 lysate by ECL immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C

Détails sur TRAP1

Antigène: TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))

Autre désignation: TRAP1 (TRAP1 Produits)

Synonymes: anticorps HSP 75, anticorps HSP75, anticorps HSP90L, anticorps TRAP-1, anticorps 2410002K23Rik, anticorps fc85a11, anticorps wu:fc85a11, anticorps TNF receptor associated protein 1, anticorps TNF receptor-associated protein 1, anticorps TRAP1, anticorps Trap1, anticorps trap1

Sujet: The 90 kDa heat shock protein (HSP90) family of proteins that play an important physiological role. HSP90 is involved in numerous cellular processes but is best known for its association with signal transduction machinery. A recently cloned homolog of HSP90 is the tumor necrosis factor receptor-associated protein (TRAP1). Like HSP90, TRAP1 is found to be associated with numerous proteins involved in diverse actions (1, 2). Immunofluorescence data has shown TRAP1 to be localized in the mitochondria of mammalian cells. This observation and the fact that TRAP1 is shown to have a mitochondrial targeting pre-sequence strongly implicates TRAP1 as a mitochondrial matrix protein (3).

ID gène: 10131

NCBI Accession: NP_057376

UniProt: Q12931