NLRP6 anticorps (AA 351-450) (HRP)

N° du produit ABIN2559654

L’anticorps Lapin Polyclonal anti-NLRP6 a été validé pour ELISA, IHC (fro) et IHC (p). Il convient pour détecter NLRP6 dans des échantillons de Souris et Rat.

Aperçu rapide pour NLRP6 anticorps (AA 351-450) (HRP) (ABIN2559654)

Antigène: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP6 est conjugé à/à la HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-NLRP6 anticorps (HRP)

Épitope: AA 351-450

Réactivité croisée: Souris, Rat

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NALP6

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur NLRP6

Antigène: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Autre désignation: NALP6

Sujet:

Synonyms: AVR, NAVR, PAN3, NALP6, PYPAF5, CLR11.4, NAVR/AVR, NACHT, LRR and PYD domains-containing protein 6, Angiotensin II/vasopressin receptor, PYRIN-containing APAF1-like protein 5, NLRP6

Background: May contribute to arginine-vasopressin (AVP)-mediated regulation of renal salt-water balance, glucose and lipid metabolism, apoptosis, and/or cell cycle. Binds arginine-vasopressin but not angiotensin II and acts as an arginine-vasopressin V2 receptor. Plays a role in modulating inflammatory responses in the colon to allow recovery from intestinal epithelial damage and limit tumorigenic potential. Protects against the development of colitis by controlling the composition of the gut microbiota by preventing colonization of the colon by harmful, inflammation-inducing bacteria such as Prevotella species. May mediate activation of CASP1 via ASC, promote activation of NF-kappa-B and stimulate cAMP accumulation (By similarity).

ID gène: 171389

UniProt: P59044

Pathways: Inflammasome