TLR4 anticorps (PE)
Aperçu rapide pour TLR4 anticorps (PE) (ABIN2567455)
Antigène
Voir toutes TLR4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- The HTA125 monoclonal antibody specifically reacts with human CD284, a 110kDA type I transmembrane signaling molecule known as the Toll-like Receptor 4 (TLR4).
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Purification
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Isotype
- IgG2a kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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Stock
- 4 °C
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Stockage commentaire
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- TLR4 (Toll-Like Receptor 4 (TLR4))
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Autre désignation
- CD284
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Sujet
- The HTA125 monoclonal antibody specifically reacts with human CD284, a 110kDA type I transmembrane signaling molecule known as the Toll-like Receptor 4 (TLR4). CD284 is an important molecule in the innate immunity response to bacterial lipoproteins. It is expressed by monocytes, macrophages, and endothelial cells. The HTA125 antibody can block Lipopolysaccharide-induced cytokine production and immunoprecipitate human TLR4.
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ID gène
- 7099
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UniProt
- O00206
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Pathways
- Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
Antigène
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