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CD45.1 anticorps (PerCP-Cy5.5)

Reactivité: Souris FACS Hôte: Souris Monoclonal A20 PerCP-Cy5.5
N° du produit ABIN2567757
  • Antigène Tous les produits CD45.1
    CD45.1 (CD45 (CD45.1 Allogen))
    Reactivité
    Souris
    Hôte
    • 56
    Souris
    Clonalité
    • 56
    Monoclonal
    Conjugué
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD45.1 est conjugé à/à la PerCP-Cy5.5
    Application
    • 51
    • 14
    • 12
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    The A20 monoclonal antibody reacts with the leukocytes of the CD45.1-expressing mouse strains (DA, SJL/J, RIII, and STS/A).
    Purification
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
    Clone
    A20
    Isotype
    IgG2a kappa
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
    Stock
    4 °C
    Stockage commentaire
    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • Antigène
    CD45.1 (CD45 (CD45.1 Allogen))
    Autre désignation
    CD45.1 (CD45.1 Produits)
    Sujet
    The A20 monoclonal antibody reacts with the leukocytes of the CD45.1-expressing mouse strains (DA, SJL/J, RIII, and STS/A). It does not cross-react with cells that express CD45.2. The CD45 Molecule is a member of the Protein Tyrosine Phosphatase (PTP) family, because its intracellular region contains two PTP domains. The extracellular region's variability is caused by different levels of glycosylation, and the splicing of the 4, 5, and 6 exons. The isoforms found in the mouse strains depend on the activation state, maturation stage and cell type, and are very important in B and T lymphocytes antigen receptor signal transduction. The A20 antibody inhibits some of the B lymphocytes responses, from CD45.1-expressing mice, to lipopolysaccharides and antigens.
    ID gène
    19264
    UniProt
    P06800
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