FGFR1/FGFR2 anticorps (pTyr463, pTyr466)

N° du produit ABIN2568142

Détail du produit anti-FGFR1/FGFR2 anticorps

Antigène: FGFR1/FGFR2 (FGFR1, FGFR2)

Épitope: pTyr463, pTyr466

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGFR1/FGFR2 est non-conjugé

Application: Western Blotting (WB)

Specificité: The antibody detects endogenous levels of FGFR1/2 only when phosphorylated at tyrosine 463/466.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: FGFR1/2 (phospho Tyr463/466) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 463/466 (S-E-Y (p)-E-L) derived from Human FGFR1/2.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détails sur FGFR1/FGFR2

Antigène: FGFR1/FGFR2 (FGFR1, FGFR2)

Autre désignation: FGFR1/2 (FGFR1/FGFR2 Produits)

Sujet: The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.

Poids moléculaire: 91 kDa

ID gène: 2260, 2263

NCBI Accession: NP_075598

UniProt: P11362, P21802