RFX1 anticorps

N° du produit ABIN2568446

Détail du produit anti-RFX1 anticorps

Antigène: RFX1 (Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RFX1 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: RFX1 antibody is human specific. At least two isoforms of RFX1 are known to exist, this antibody will detect both isoforms.

Purification: RFX1 antibody is affinity chromatography purified via peptide column.

Immunogène: RFX1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human RFX1

Isotype: IgG

Information d'application

Indications d'application: RFX1 antibody can be used for detection of RFX1 by Western blot at 1 - 2 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: RFX1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: RFX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur RFX1

Antigène: RFX1 (Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1))

Autre désignation: RFX1 (RFX1 Produits)

Synonymes: anticorps EFC, anticorps RFX, anticorps AI047719, anticorps AI385641, anticorps zgc:162914, anticorps regulatory factor X1, anticorps regulatory factor X, 1 (influences HLA class II expression), anticorps regulatory factor X, 1a (influences HLA class II expression), anticorps RFX1, anticorps Rfx1, anticorps rfx1a

Sujet: RFX1 is a member of the regulatory factor X protein family, which are transcription factors that contain a highly-conserved winged helix DNA binding domain and the D region found in the C-terminal part of these proteins which facilitates dimerization (1,2). RFX1 is structurally related to regulatory factors X2, X3, X4, and X5 (3). RFX1 is a regulatory factor essential for MHC class II genes expression and can bind to an inverted repeat that is required for expression of hepatitis B virus genes (4). Recent study identifies RFX1 may play a tumor suppressor role in HCC as autophagy mediator (5).

Poids moléculaire: Predicted: 108 kDa

Observed: 125 kDa

ID gène: 5989

NCBI Accession: NP_002909

UniProt: P22670