RSK1/2/3/4 (pSer221), (pSer227), (Ser218), (Ser232) anticorps

N° du produit ABIN2568448

Détail du produit

Antigène: RSK1/2/3/4

Épitope: pSer221, pSer227, Ser218, Ser232

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Specificité: The antibody detects endogenous levels of RSK1/2/3/4 only when phosphorylated at serine 221/227/218/232.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: RSK1/2/3/4 (phospho Ser221/227/S218/232) antibody was raised against a peptide sequence around phosphorylation site of Serine 221/227/218/232 (A-Y-S (p)-F-C) derived from Human RSK1/2/3/4.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détail du antigène

Antigène: RSK1/2/3/4

Sujet: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway.

Poids moléculaire: 85 kDa

ID gène: 6195, 6197, 6196

NCBI Accession: NP_002944

UniProt: Q15418, P51812, Q15349, Q9UK32