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SREBF1 anticorps (pSer439)
SREBF1
Reactivité: Humain, Rat
WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN2568461
Détail du produit anti-SREBF1 anticorps
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Antigène
Voir toutes SREBF1 Anticorps
SREBF1
(Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
Épitope
Tous les épitopes à travers SREBF1 Anticorps.
pSer439
Reactivité
Toutes les réactivités sur SREBF1 Anticorps
Humain, Rat
Hôte
Toutes les hôtes sur SREBF1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur SREBF1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers SREBF1 Anticorps
Cet anticorp SREBF1 est non-conjugé
Application
Tous les applications à travers SREBF1 Anticorps.
Western Blotting (WB)
Specificité
The antibody detects endogenous level of SREBP-1 only when phosphorylated at serine 439.
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Immunogène
SREBP-1 (phospho Ser439) antibody was raised against a peptide sequence around phosphorylation site of serine439 (Q-S-S (p)-P-L) derived from Human SREBP-1 .
Isotype
IgG
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Information d'application
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Indications d'application
Western Blot: 1:500~1:1000
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store antibody at -20°C for up to one year.
Détails sur SREBF1
(cache)
Antigène
SREBF1
(Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
Autre désignation
SREBP-1 (SREBF1 Produits )
Synonymes
anticorps SREBP-1c, anticorps SREBP1, anticorps bHLHd1, anticorps ADD-1, anticorps ADD1, anticorps D630008H06, anticorps SREBP-1, anticorps SREBP-1a, anticorps SREBP1c, anticorps Srebp1, anticorps SCREBP1, anticorps SREBP-1C, anticorps SREBF1, anticorps srebp1, anticorps sterol regulatory element binding transcription factor 1, anticorps sterol regulatory element binding transcription factor 1 L homeolog, anticorps sterol regulatory element binding protein-1, anticorps Sterol regulatory element Binding Protein, anticorps SREBF1, anticorps Srebf1, anticorps srebf1.L, anticorps SREBP-1, anticorps srebf1, anticorps sbp-1
Sujet
Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway By similarity. Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3').
Poids moléculaire
122 kDa
ID gène
6720
NCBI Accession
NP_001005291
UniProt
P36956
Pathways
AMPK Signaling , Caspase Cascade in Apoptosis , Negative Regulation of Hormone Secretion , Regulation of Lipid Metabolism by PPARalpha
Vus récemment
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