Prothrombin anticorps

N° du produit ABIN264058

Cet anticorps Souris Monoclonal détecte spécifiquement Prothrombin dans WB et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour Prothrombin anticorps (ABIN264058)

Antigène: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Prothrombin est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: BDI095

Détail du produit anti-Prothrombin anticorps

Specificité: This antibody binds Prothrombin, Prethrombin 1 and fragment 2 (residues 156-271) in solid-phase ELISA. Blots Human Prothrombin in Western blot.

Attributs du produit: Synonyms: Coagulation factor II

Purification: Gel filtration and Ion Exchange Chromatography

Immunogène: Purified Human Prothrombin

Isotype: IgG2a

Information d'application

Indications d'application: ELISA. Western blot. A starting range of 1-5g/mL is recommended.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with distilled water

Concentration: 1.0 mg/mL (prior to lyophilization)

Buffer: 10 mM Sodium phosphate, 0.15 M Sodium Chloride, pH 7.4 containing 0.01 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at -20 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one monthor (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Prothrombin

Antigène: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Autre désignation: Prothrombin (F2)

Sujet: Prothrombin (Factor 2 in the coagulation cascade) is proteolytically cleaved at two sites by Factor Xa to form thrombin (Factor IIa) in an important step of the coagulation cascade which ultimately results in the stemming of blood loss. Thrombin being the single most important constituent of the coagulation cascade in terms of its feedback activation roles. Prothrombin also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in Prothrombin lead to various forms of thrombosis and dysprothrombinemia.Synonyms: Coagulation factor II

ID gène: 2147

UniProt: P00734

Pathways: Système du Complément, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling