PPP2R5D
Reactivité: Humain, Rat
WB, IP
Hôte: Souris
Monoclonal
H5-D12
unconjugated
Indications d'application
Western Blotting. Immunofluorescence. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Buffer
Phosphate buffered saline with 0.08 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
-20 °C
Stockage commentaire
The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
PP2A is a heterotrimeric phosphatase, ccomposed of A, B and C subunits. The structural A and catalytic C subunits form the constitutive core of the enzyme, which associates with one of a large number of regulatory B subunits. Three families of B subunits have been identified thus far. The prototypical B (or PR55) family of subunits is encoded by three genes, Ba, Bb and Bg . The B' (or B56) family consists of at least seven splice variants derived from five genes. RNA's for the two members of the B family, PR72 and PR130, arise by alternative splicing or use of alternate transcription start sites from the same gene. Primary structures as well as functions of B and B' subunits are conserved from yeast to mammals. Bd is a novel isoform of the B class of PP2A regulatory subunits. It is widely expressed in rat tissues and appears to be involved in targeting PP2A to the cytosolic compartment.Synonyms: PP2A B subunit B'delta isoform, PP2A B subunit B56 delta isoform, PP2A B subunit PR61 delta isoform, PP2A B subunit R5 delta isoform, Protein phosphatase 2A, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform