PLAUR anticorps

N° du produit ABIN2650943

Détail du produit anti-PLAUR anticorps

Antigène: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLAUR est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human PLAUR

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Commentaires:

Expressed in neurons of the rolandic area of the brain (at protein level), Expressed in the brain

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur PLAUR

Antigène: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Autre désignation: PLAUR (PLAUR Produits)

Synonymes: anticorps Cd87, anticorps u-PAR, anticorps uPAR, anticorps CD87, anticorps U-PAR, anticorps UPAR, anticorps URKR, anticorps Par, anticorps Plaur3, anticorps uPAR-2, anticorps uPAR-3, anticorps PLAUR, anticorps plasminogen activator, urokinase receptor, anticorps Plaur, anticorps PLAUR

Sujet: This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.

Poids moléculaire: 36.978 kDa

ID gène: 5329

UniProt: Q03405

Pathways: Inositol Metabolic Process