ROBO1 anticorps

N° du produit ABIN265227

Détail du produit anti-ROBO1 anticorps

Antigène: ROBO1 (Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ROBO1 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects Roundabout homolog 1 / ROBO1, widely expressed, with exception of kidney.

Purification: Purified

Immunogène: Synthetic peptide derived from human ROBO1 protein

Information d'application

Indications d'application: Western Blot (1-5 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.

Détails sur ROBO1

Antigène: ROBO1 (Roundabout, Axon Guidance Receptor, Homolog 1 (ROBO1))

Autre désignation: ROBO1 (ROBO1 Produits)

Synonymes: anticorps DUTT1, anticorps SAX3, anticorps AW494633, anticorps AW742721, anticorps Gm310, anticorps ROBO1, anticorps dutt1, anticorps roundabout, anticorps sax3, anticorps MGC122264, anticorps roundabout-1, anticorps roundabout guidance receptor 1, anticorps roundabout, axon guidance receptor, homolog 1 (Drosophila), anticorps roundabout guidance receptor 1 L homeolog, anticorps ROBO1, anticorps Robo1, anticorps robo1, anticorps robo1.L

Sujet: Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development. Defects in ROBO1 may be a cause of breast and lung cancer. ROBO1 maps within a region of overlapping homozygous deletions characterized in both small cell lung cancer cell lines (SCLC) and in a breast cancer cell line.Synonyms: DUTT1, Deleted in U Twenty Twenty, ROBO-1, Roundabout homolog 1

ID gène: 6091

NCBI Accession: NP_002932

UniProt: Q9Y6N7

Pathways: Positive Regulation of Endopeptidase Activity