COL4A3BP anticorps

N° du produit ABIN265284

Détail du produit anti-COL4A3BP anticorps

Antigène: COL4A3BP (Collagen, Type IV, alpha 3 (Goodpasture Antigen) Binding Protein (COL4A3BP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COL4A3BP est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects CERTL.

Purification: Purified

Immunogène: Synthetic peptide derived from human CERTL protein

Isotype: IgG

Information d'application

Indications d'application: Western Blot (5-10 μg/mL). Positive control: ovary.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.

Détails sur COL4A3BP

Antigène: COL4A3BP (Collagen, Type IV, alpha 3 (Goodpasture Antigen) Binding Protein (COL4A3BP))

Autre désignation: COL4A3BP (COL4A3BP Produits)

Synonymes: anticorps COL4A3BP, anticorps 2810404O15Rik, anticorps 9230101K08Rik, anticorps AU016711, anticorps CERT, anticorps GPBP, anticorps col4a3bp, anticorps wu:fc37f11, anticorps zgc:92147, anticorps CERTL, anticorps STARD11, anticorps cert, anticorps certl, anticorps cetp, anticorps gpbp, anticorps stard11, anticorps collagen type IV alpha 3 binding protein, anticorps collagen, type IV, alpha 3 (Goodpasture antigen) binding protein, anticorps collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a, anticorps collagen, type IV, alpha 3 (Goodpasture antigen) binding protein L homeolog, anticorps COL4A3BP, anticorps Col4a3bp, anticorps col4a3bpa, anticorps col4a3bp.L

Sujet: CERT mediates the ATP-dependent ER-to-Golgi transfer of ceramide in a non-vesicular manner. The biosynthesis of lipids involves steps that occur in different intracellular compartments. The movement of lipids within these compartments is important in lipid-mediated signalling. Human CERT is identical to a splice variant of human Goodpasture antigen-binding protein (GPBP26). CERT contains a phosphoinositide-binding pleckstrin-homology (PH) domain (which targets CERT to the Golgi by binding phosphatidylinositol-4-phosphate (PtdIns4P)), a middle region, and a putative lipid-transfer-catalysing domain called START. CERT and CERTL can specifically extract ceramide from phospholipid bilayers in a START-domain-dependent manner. CERT interacts with ER membranes and specifically extracts ceramide. CERT catalyses both the specific extraction of ceramide from donor vesicles and its transfer to acceptor vesicles. CERT can associate with the Golgi in a PtdIns4P dependent manner.Synonyms: CERT, Ceramide transfer protein, Collagen type IV alpha-3-binding protein, GPBP, Goodpasture antigen-binding protein, STARD11, START domain-containing protein 11, StAR-related lipid transfer protein 11, StARD11, hCERT

ID gène: 10087

NCBI Accession: NP_001123577

UniProt: Q9Y5P4