CLDN10 anticorps

N° du produit ABIN265359

Détail du produit anti-CLDN10 anticorps

Antigène: CLDN10 (Claudin 10 (CLDN10))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLDN10 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects endogenous levels of Claudin-10 / CLDN10 protein (region surrounding Asn217).

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CLDN10

Antigène: CLDN10 (Claudin 10 (CLDN10))

Autre désignation: Claudin-10 / CLDN10 (CLDN10 Produits)

Synonymes: anticorps si:busm1-52i16.3, anticorps si:dz52i16.3, anticorps CLDN10, anticorps DKFZp469F1626, anticorps CPETRL3, anticorps OSP-L, anticorps 6720456I16Rik, anticorps Cldn10a, anticorps Cldn10b, anticorps D14Ertd728e, anticorps claudin 10a, anticorps claudin 10, anticorps cldn10a, anticorps CLDN10, anticorps Cldn10

Sujet: The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the Claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Emerging evidence suggests that the Claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions.Synonyms: OSP-Like Protein, OSPL

Poids moléculaire: approx. 25 kDa

ID gène: 9071

NCBI Accession: NP_008915

UniProt: P78369

Pathways: Hepatitis C