GRIK1 anticorps

N° du produit ABIN265438

Détail du produit anti-GRIK1 anticorps

Antigène: GRIK1 (Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of GluR5 protein. (region surrounding Leu12)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: ELISA: 1: 1 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GRIK1

Antigène: GRIK1 (Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1))

Autre désignation: Glutamate Receptor 5 / GLUR5 (GRIK1 Produits)

Synonymes: anticorps GRIK1, anticorps grik1, anticorps fv36b03, anticorps wu:fv36b03, anticorps EAA3, anticorps EEA3, anticorps GLR5, anticorps GLUR5, anticorps GluK1, anticorps A830007B11Rik, anticorps D16Ium24, anticorps D16Ium24e, anticorps GluK5, anticorps Glur-5, anticorps Glur5, anticorps Glurbeta1, anticorps GluR5, anticorps glutamate ionotropic receptor kainate type subunit 1, anticorps glutamate receptor, ionotropic, kainate 1a, anticorps glutamate receptor, ionotropic, kainate 1, anticorps GRIK1, anticorps grik1a, anticorps Grik1

Sujet: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamategated, caution-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution.Synonyms: EAA3, Excitatory amino acid receptor 3, GRIK1, Glutamate receptor ionotropic kainate 1

Poids moléculaire: approx. 100 kDa

ID gène: 2897

NCBI Accession: NP_000821

UniProt: P39086

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity