GRIK2 anticorps

N° du produit ABIN265439

Détail du produit anti-GRIK2 anticorps

Antigène: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIK2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of GluR6 protein. (region surrounding Ala865)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 1 5000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur GRIK2

Antigène: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Autre désignation: Glutamate Receptor 6 / GLUR6 (GRIK2 Produits)

Synonymes: anticorps GRIK5, anticorps eaa4, anticorps glr6, anticorps gluk6, anticorps glur6, anticorps grik2, anticorps mrt6, anticorps GluR6, anticorps grik2-A, anticorps EAA4, anticorps GLR6, anticorps GLUK6, anticorps GLUR6, anticorps GluK2, anticorps MRT6, anticorps AW124492, anticorps Glur-6, anticorps Glur6, anticorps Glurbeta2, anticorps GRIK2, anticorps glutamate ionotropic receptor kainate type subunit 2, anticorps glutamate receptor, ionotropic, kainate 2 L homeolog, anticorps glutamate receptor, ionotropic, kainate 2, anticorps glutamate receptor, ionotropic, kainate 2 (beta 2), anticorps GRIK2, anticorps grik2.L, anticorps grik2, anticorps Grik2

Sujet: The mGluR proteins (metabotropic glutamate receptors) are members of the G protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR-1 and mGluR-5 are mediated by a G protein that activates a phosphatidylinositolcalcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight subtypes of mGluR have an activity mediated by a G protein that inhibits adenylate cyclase activity. mGluR-6 is expressed in the synapses of bipolar cell dendrites. This receptor is involved in mediating synaptic transmission from rod and cone photoreceptors to other neurons.Synonyms: EAA4, Excitatory amino acid receptor 4, GRIK2, Glutamate receptor ionotropic kainate 2

Poids moléculaire: approx. 100 kDa

ID gène: 2898

NCBI Accession: NP_001159719

UniProt: Q13002

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity