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NOTCH3 anticorps (Alexa Fluor 647)
NOTCH3
Reactivité: Souris
FACS
Hôte: Hamster
Monoclonal
HMN3-133
Alexa Fluor 647
N° du produit ABIN2657987
Détail du produit anti-NOTCH3 anticorps (Alexa Fluor 647)
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Antigène
Voir toutes NOTCH3 Anticorps
NOTCH3
(Notch 3 (NOTCH3))
Reactivité
Toutes les réactivités sur NOTCH3 Anticorps
Souris
Hôte
Toutes les hôtes sur NOTCH3 Anticorps
Hamster
Clonalité
Toutes les clonalités sur NOTCH3 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers NOTCH3 Anticorps
Cet anticorp NOTCH3 est conjugé à/à la Alexa Fluor 647
Application
Tous les applications à travers NOTCH3 Anticorps.
Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
Clone
HMN3-133
Isotype
IgG
Top Product
Discover our top product NOTCH3 Anticorps primaire
Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Protect from prolonged exposure to light. Do not freeze.
Stock
4 °C
Stockage commentaire
The antibody solution should be stored undiluted between 2°C and 8°C
Détails sur NOTCH3
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Antigène
NOTCH3
(Notch 3 (NOTCH3))
Autre désignation
Notch 3 (NOTCH3 Produits )
Synonymes
anticorps CADASIL, anticorps CASIL, anticorps IMF2, anticorps AW229011, anticorps N3, anticorps hpbk, anticorps fa14b08, anticorps notch5, anticorps wu:fa14b08, anticorps notch 3, anticorps NOTCH3, anticorps Notch3, anticorps notch3
Sujet
The Notch receptors are highly conserved from invertebrates to mammals.While Notch1 and Notch 2 exhibit the highest structural similarity among the four mammalian Notch receptors. Notch 3 has a number of structural and functional differences.The binding of Notch 3 to its ligands results in the proteolysis of Notch and movement of intracellular portions of Notch into the nucleus.This translocation triggers a series of signaling process.Notch 3 is primarily expressed in adult arterial smooth muscle cells.Notch 3 gene mutation can cause CADASIL, an inherited early stroke syndrome.
Pathways
Signalisation Notch
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