anticorps CD64, anticorps CD64A, anticorps FCRI, anticorps IGFR1, anticorps FcgammaRI, anticorps Fcgr1, anticorps Fcgr1b, anticorps AI323638, anticorps AV092959, anticorps IGGHAFC, anticorps FCGR1A, anticorps Fc fragment of IgG receptor Ia, anticorps Fc receptor, IgG, high affinity I, anticorps FCGR1A, anticorps Fcgr1a, anticorps Fcgr1
Sujet
CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).