FCGR1A anticorps (Pacific Blue)

N° du produit ABIN2662300

Détail du produit anti-FCGR1A anticorps (Pacific Blue)

Antigène: FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FCGR1A est conjugé à/à la Pacific Blue

Application: Flow Cytometry (FACS)

Réactivité croisée: Chimpanzé, Babouin, Cynomolgus, Macaque rhésus, Capuchin Monkey, Squirrel Monkey (Saimiri spec.)

Purification: The antibody was purified by affinity chromatography, and conjugated with Pacific Blue™ under optimal conditions. The solution is free of unconjugated Pacific Blue™.

Clone: 10-1

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur FCGR1A

Antigène: FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))

Autre désignation: CD64 (FCGR1A Produits)

Synonymes: anticorps CD64, anticorps CD64A, anticorps FCRI, anticorps IGFR1, anticorps FcgammaRI, anticorps Fcgr1, anticorps Fcgr1b, anticorps AI323638, anticorps AV092959, anticorps IGGHAFC, anticorps FCGR1A, anticorps Fc fragment of IgG receptor Ia, anticorps Fc receptor, IgG, high affinity I, anticorps FCGR1A, anticorps Fcgr1a, anticorps Fcgr1

Sujet: CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process