TCR V beta 11 anticorps (PE)

N° du produit ABIN2662861

Détail du produit

Antigène: TCR V beta 11

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: PE

Application: Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)

Purification: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Clone: RR3-15

Isotype: IgG2b kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détail du antigène

Antigène: TCR V beta 11

Autre désignation: TCR V Beta11

Sujet: T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR-β is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex. The CD3/TCR complex plays a key role in antigen recognition, signal transduction, and T cell activation. V β 11-bearing T cells are largely absent from strains of mice that express MHC class II molecule I-E. It has been demonstrated that the expression of I-E molecule is necessary for the clonal deletion of V beta 11-bearing T cells, but not sufficient for the clonal elimination of V beta 11-bearing T cells.