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CD276 anticorps (PE)

CD276 Reactivité: Souris FACS Hôte: Rat Monoclonal RTAA15 PE
N° du produit ABIN2663287
  • Antigène Voir toutes CD276 Anticorps
    CD276
    Reactivité
    • 64
    • 39
    • 10
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    Souris
    Hôte
    • 46
    • 18
    • 10
    • 1
    Rat
    Clonalité
    • 39
    • 35
    • 1
    Monoclonal
    Conjugué
    • 45
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD276 est conjugé à/à la PE
    Application
    • 52
    • 26
    • 24
    • 14
    • 13
    • 12
    • 9
    • 9
    • 9
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    Clone
    RTAA15
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product CD276 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Protect from prolonged exposure to light. Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Antigène
    CD276
    Autre désignation
    CD276 (CD276 Produits)
    Synonymes
    anticorps sc:d0645, anticorps zgc:158279, anticorps 6030411F23Rik, anticorps AU016588, anticorps B7RP-2, anticorps B7h3, anticorps B7H3, anticorps 4Ig-B7-H3, anticorps B7-H3, anticorps CD276 molecule, anticorps CD276 molecule S homeolog, anticorps CD276 antigen, anticorps Cd276 molecule, anticorps CD276, anticorps cd276.S, anticorps cd276, anticorps Cd276
    Sujet
    B7-H3 is a member of the B7 gene family. It has 88 % amino acid sequence identity with human B7-H3. It is mostly expressed on professional APCs, including B cells, macrophages, and dendritic cells. Its expression on dendritic cells appears to be up-regulated by LPS. B7-H3 protein inhibits T cell activation and cytokine production. It was reported that monoclonal antibody against B7-H3 enhanced T cell proliferation in vitro and led to exacerbated EAE in vivo. Therefore, B7-H3 may be a negative regulator on T cell activation and function.
    Pathways
    Cancer Immune Checkpoints
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