Galectin 3 anticorps (AA 151-251)

N° du produit ABIN2665255

Détail du produit anti-Galectin 3 anticorps

Antigène: Galectin 3 (LGALS3)

Épitope: AA 151-251

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Galectin 3 est non-conjugé

Application: Immunoprecipitation (IP)

Purification: The antibody was purified by affinity chromatography.

Clone: Gal397

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur Galectin 3

Antigène: Galectin 3 (LGALS3)

Autre désignation: Mac-2 (LGALS3 Produits)

Synonymes: anticorps CBP 35, anticorps Gal-3, anticorps Galectin-3, anticorps leg3, anticorps galactoside-binding, anticorps galectin-3, anticorps lectin, anticorps soluble, anticorps CBP35, anticorps GAL3, anticorps GALBP, anticorps GALIG, anticorps L31, anticorps LGALS2, anticorps MAC2, anticorps MGC52947, anticorps MGC75803, anticorps LGALS3, anticorps gal-3, anticorps GBP, anticorps L-34, anticorps Mac-2, anticorps gal3, anticorps galectin 3, anticorps Galectin-3, anticorps avian beta-defensin 3, anticorps lectin, galactoside-binding, soluble, 3 L homeolog, anticorps lectin, galactoside-binding, soluble, 3, anticorps galectin 2, anticorps lectin, galactose binding, soluble 3, anticorps LGALS3, anticorps leg3, anticorps AvBD3, anticorps lgals3.L, anticorps lgals3, anticorps LGALS2, anticorps Lgals3

Classe de substances: Chemical

Sujet: Galectin-3 (galactose-specific lectin 3) is a 30-32 kD glycoprotein, also know as Mac-2, Gal-3, RL-29, galactose-specific lectin 3, CBP-35, L-34, and εBP. It is a member of animal β-galactoside-binding protein family that is expressed in cell nucleus, cytoplasm, plasma membrane, or extracellular matrix by variety of tumor cells, monocytes/macrophages, epithelial cells, Kupffer cells, and dendritic cells. Galectin-3 contains carbohydrate recognition domains and binds to β-galactoside residues bearing glycoproteins, such as as IgE, IgA, galactose, casein kinase I, laminin, mucin, LAMPs, and CD66. Galectin-3 is an adhesion molecule and plays an important role in regulation of cell proliferation, differentiation and tumor cell metastasis. Galectin-3 structurely possesses NWGR motif that is conserved in BH-1 domain of BCL-2 family and functions as an anti-apoptotic molecule.

Pathways: Signalisation RTK