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Nanog anticorps

NANOG Reactivité: Humain BCA Hôte: Souris Monoclonal 16H3A48 unconjugated
N° du produit ABIN2666251
  • Antigène Voir toutes Nanog (NANOG) Anticorps
    Nanog (NANOG) (Nanog Homeobox (NANOG))
    Reactivité
    • 132
    • 60
    • 23
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 121
    • 17
    • 3
    • 1
    Souris
    Clonalité
    • 116
    • 26
    Monoclonal
    Conjugué
    • 77
    • 9
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp Nanog est non-conjugé
    Application
    • 110
    • 59
    • 43
    • 43
    • 26
    • 26
    • 19
    • 18
    • 18
    • 15
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Biochemical Assay (BCA)
    Purification
    The antibody was purified by affinity chromatography.
    Clone
    16H3A48
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product NANOG Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Upon receipt, store undiluted at 4°C
  • Antigène
    Nanog (NANOG) (Nanog Homeobox (NANOG))
    Autre désignation
    Nanog (NANOG Produits)
    Synonymes
    anticorps 2410002E02Rik, anticorps ENK, anticorps ecat4, anticorps NANOG, anticorps hacp, anticorps wu:fd19e04, anticorps wu:fd20a07, anticorps zgc:193933, anticorps Nanog homeobox, anticorps nanog homeobox, anticorps Nanog, anticorps NANOG, anticorps nanog
    Sujet
    NANOG is a homeodomain-containing transcription factor that is essential for early embryonic development. It is primarily expressed in pluripotent embryonic stem (ES) cells and cancer cell lines, maintaining undifferentiated statuses of the cells and is downregulated upon differentiation. Si-RNA mediated knockdown of NANOG in ES cells induces lineage differentiation. Overexpression of NANOG allows for the leukemia inhibitory factor (LIF)-independent selfrenewal in undifferentiated ES cells. Nanog functionally works with OCT4 and SOX2 to support pluripotency and selfrenewal in ES cells and the expression of NANOG is regulated by OCT4/SOX2 heterodimers. Expression of NANOG has been detected in several types of tumor cells. The expression level of NANOG in cancer cells has been shown to be correlated with the malignancy of cancers.
    Pathways
    Stem Cell Maintenance
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