Retinoblastoma Binding Protein 8 anticorps (AA 620-897)

N° du produit ABIN2668263

Cet anticorps Souris Monoclonal détecte spécifiquement Retinoblastoma Binding Protein 8 dans WB, IP, ICC et IF. Il présente une réactivité envers Humain et a été mentionné dans 6+ publications.

Aperçu rapide pour Retinoblastoma Binding Protein 8 anticorps (AA 620-897) (ABIN2668263)

Antigène: Retinoblastoma Binding Protein 8 (RBBP8)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoblastoma Binding Protein 8 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: 14-1

Détail du produit anti-Retinoblastoma Binding Protein 8 anticorps

Épitope: AA 620-897

Purification: Protein A Chromatography

Immunogène: This CtIP antibody was raised against a recombinant protein corresponding to amino acid residues 620-897 of human CtIP.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Stock: -20 °C

Stockage commentaire: Antibodies in solution can be stored at -20 °C for 2 years.

Date de péremption: 6 months

Références pour anticorps anti-Retinoblastoma Binding Protein 8 (ABIN2668263)

Onyango, Howard, Neherin, Yanez, Stark: "Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination." dans: Nucleic acids research, Vol. 44, Issue 12, pp. 5702-16, (2016) (PubMed).

Bakr, Köcher, Volquardsen, Petersen, Borgmann, Dikomey, Rothkamm, Mansour: "Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1." dans: Oncotarget, Vol. 7, Issue 36, pp. 57679-57693, (2016) (PubMed).

Zhou, Caron, Legube, Paull: "Quantitation of DNA double-strand break resection intermediates in human cells." dans: Nucleic acids research, Vol. 42, Issue 3, pp. e19, (2014) (PubMed).

Makharashvili, Tubbs, Yang, Wang, Barton, Zhou, Deshpande, Lee, Lobrich, Sleckman, Wu, Paull: "Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection." dans: Molecular cell, Vol. 54, Issue 6, pp. 1022-33, (2014) (PubMed).

Zhang, Jasin: "An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway." dans: Nature structural & molecular biology, Vol. 18, Issue 1, pp. 80-4, (2011) (PubMed).

Yu, Fu, Lai, Baer, Chen: "BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP." dans: Genes & development, Vol. 20, Issue 13, pp. 1721-6, (2006) (PubMed).

Détails sur Retinoblastoma Binding Protein 8

Antigène: Retinoblastoma Binding Protein 8 (RBBP8)

Autre désignation: CtIP

Poids moléculaire: 120 kDa

ID gène: 5932

Pathways: Cycle Cellulaire, Réparation de l'ADN