Prelamin A (C-Term), (cleaved), (farnesylated) anticorps

N° du produit ABIN2669376

Détail du produit

Antigène: Prelamin A

Épitope: C-Term, cleaved, farnesylated

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunofluorescence (IF)

Specificité: Anti cleaved farnesylated prelamin A polyclonal antibody detects carboxymethylated prelamin A harbouring the farnesyl residue. This antibody also recognizes progerin, the truncated form of prelamin A found in HutchinsonGilford Progeria Syndrome cells, and does not cross react with mature lamin A.

Attributs du produit: The antibody is able to detect cleaved farnesylated prelamin A, while it does not recognize either full-length prelamin A or mature lamin A. This antibody can be used for the discrimination of prelamin A forms and to check the efficacy of potential therapeutic compounds acting on prelamin A processing.

Purification: Polyclonal immunoglobulins purified by protein A affinity chromatography and stabilized with 5% of glycerol.

Immunogène: Farnesylated prelamin A C-terminus peptide

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

methanol fixing is suggested

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in 100 mM sodium citrate, 50 mM Tris and 0.05 % v/v glycerol

Stock: 4 °C

Détail du antigène

Antigène: Prelamin A