Prelamin A (C-Term) anticorps

N° du produit ABIN2669375

Détail du produit

Antigène: Prelamin A

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunofluorescence (IF), ELISA, Western Blotting (WB)

Specificité: Anti prelamin A polyclonal antibody detects fulllength prelamin A which has not yet undergone to proteolytic steps, both in its nonfarnesylated and in its farnesylated form. The farnesylated form of fulllength prelamin A is labelled by antibody with lower efficiency. The antibody does not cross react with mature lamin A.

Attributs du produit: Several laminopathies are characterized by anomalous accumulation of prelamin A. This polyclonal antibody is able to detect full-lenght prelamin A, while it does not recognize either mature lamin A or cleaved prelamin A intermediates.

Purification: Polyclonal immunoglobulins purified by protein A affinity chromatography and stabilized with 5% of glycerol.

Immunogène: Prelamin A C-terminus peptide

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in 100 mM sodium citrate, 50 mM Tris and 0.05 % v/v glycerol

Stock: 4 °C

Détail du antigène

Antigène: Prelamin A