Endoglin anticorps

N° du produit ABIN2688879

Détail du produit anti-Endoglin anticorps

Antigène: Endoglin (ENG)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Endoglin est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc))

Marque: BD Pharmingen™

Attributs du produit: The 266 monoclonal antibody specifically binds to CD105. CD105 presents an integral membrane homodimer protein with subunits of 95 kDa found on vascular endothelial cells and syncytiotrophoblasts of placenta. CD105 is weakly expressed on stromal fibroblasts. It is also expressed on U937 cells, activated macrophages, and mesenchymal stem cells. CD105 is a component of the TGF-β receptor system in human umbilical vein endothelial cells and binds TGF-β1 and TGF-β3 with high affinity but does not bind toTGF-β2. Expression of CD105 is increased on activated endothelium in tissues undergoing angiogenesis, such as in tumors, or in cases of wound healing or dermal inflammation.

BD Pharmingen™ Purified Mouse Anti-Human CD105 - Purified - Clone 266 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Human Umbilical Vein Endothelial Cells

Clone: 266

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-Endoglin (ABIN2688879)

Lastres, Bellon, Cabañas, Sanchez-Madrid, Acevedo, Gougos, Letarte, Bernabeu: "Regulated expression on human macrophages of endoglin, an Arg-Gly-Asp-containing surface antigen." dans: European journal of immunology, Vol. 22, Issue 2, pp. 393-7, (1992) (PubMed).

Détails sur Endoglin

Antigène: Endoglin (ENG)

Autre désignation: CD105 (ENG Produits)

Synonymes: anticorps ENG, anticorps MGC137842, anticorps DKFZp469D0419, anticorps END, anticorps HHT1, anticorps ORW1, anticorps AI528660, anticorps AI662476, anticorps CD105, anticorps S-endoglin, anticorps endoglin, anticorps ENG, anticorps Eng

Sujet: Synonyms: Endoglin, ENG, END, HHT1, ORW, ORW1