CD161 anticorps

N° du produit ABIN2689009

Détail du produit anti-CD161 anticorps

Antigène: CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD161 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Marque: BD Pharmingen™

Attributs du produit: Reacts with an 80 kD disulfide-linked homodimer, type II membrane glycoprotein, also referred to as NKR-P1A. CD161 is expressed on most NK cells and on subsets of CD4+ and CD8+ T cells. Reports indicate that CD161 is expressed preferentially on CD45RO+ T cells, however, it can be found on a subset of thymocytes and fetal liver T cells. Its function has not been fully elucidated, but reports indicate that NKR-P1A may serve as a specific receptor for some NK cell targets. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood lymphocytes analyzed on a FACScan

BD Pharmingen™ Purified Mouse Anti-Human CD161 - Purified - Clone DX12 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: DX12

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-CD161 (ABIN2689009)

Bennett, Zatsepina, Zamai, Azzoni, Mikheeva, Perussia: "Definition of a natural killer NKR-P1A+/CD56-/CD16- functionally immature human NK cell subset that differentiates in vitro in the presence of interleukin 12." dans: The Journal of experimental medicine, Vol. 184, Issue 5, pp. 1845-56, (1996) (PubMed).

Ryan, Niemi, Nakamura, Seaman: "NKR-P1A is a target-specific receptor that activates natural killer cell cytotoxicity." dans: The Journal of experimental medicine, Vol. 181, Issue 5, pp. 1911-5, (1995) (PubMed).

Lanier, Allison, Phillips: "Correlation of cell surface antigen expression on human thymocytes by multi-color flow cytometric analysis: implications for differentiation." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 137, Issue 8, pp. 2501-7, (1986) (PubMed).

Détails sur CD161

Antigène: CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))

Autre désignation: CD161 (KLRB1 Produits)

Synonymes: anticorps NKR-P1, anticorps KLRB1, anticorps 4930431A04Rik, anticorps Gm4696, anticorps Klrb1g, anticorps Klrb6, anticorps Ly-55, anticorps Ly55, anticorps NKR-P1G, anticorps Nkrp-1e, anticorps Nkrp1g, anticorps CD161, anticorps CLEC5B, anticorps NKR, anticorps NKR-P1A, anticorps NKRP1A, anticorps hNKR-P1A, anticorps Klrb1d, anticorps Klrb1f, anticorps Nkr-p1e, anticorps killer cell lectin like receptor B1, anticorps killer cell lectin-like receptor subfamily B member 1, anticorps killer cell lectin-like receptor subfamily B, member 1, anticorps KLRB1, anticorps Klrb1