CD51/CD61 anticorps

N° du produit ABIN2689327

Détail du produit anti-CD51/CD61 anticorps

Antigène: CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))

Reactivité: Humain, Lapin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD51/CD61 est non-conjugé

Application: Flow Cytometry (FACS)

Marque: BD Pharmingen™

Attributs du produit: Reacts with the integrin αvβ3 heterodimeric complex (CD51/CD61), which is expressed in high amounts on osteoclasts, endothelial cells, melanoma cells, and in very low amounts on platelets. This antibody has been reported to cross-react with chicken and rabbit, but not with rat, αvβ3. The integrin αvβ3, often referred to as the vitronectin receptor, binds several ligands in addition to vitronectin, and its binding to some ligands has been reported to be inhibited by the 23C6 mAb. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of M21 (melanoma) cells analyzed by flow cytometry

BD Pharmingen™ Purified Mouse Anti-Human CD51/CD61 - Purified - Clone 23C6 - Isotype Mouse IgG1, κ - Reactivity Hu, Rab - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: 23C6

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-CD51/CD61 (ABIN2689327)

Nesbitt, Nesbit, Helfrich, Horton: "Biochemical characterization of human osteoclast integrins. Osteoclasts express alpha v beta 3, alpha 2 beta 1, and alpha v beta 1 integrins." dans: The Journal of biological chemistry, Vol. 268, Issue 22, pp. 16737-45, (1993) (PubMed).

Détails sur CD51/CD61

Antigène: CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))

Autre désignation: CD51/CD61 (ITGAV/ITGB3 Produits)

Synonymes: anticorps CD51, anticorps MSK8, anticorps VNRA, anticorps VTNR, anticorps integrin subunit alpha V, anticorps ITGAV