Selectin E/CD62e anticorps (Biotin)

N° du produit ABIN2689357

Détail du produit anti-Selectin E/CD62e anticorps (Biotin)

Antigène: Selectin E/CD62e (SELE) (Selectin E (SELE))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Selectin E/CD62e est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Marque: BD Pharmingen™

Attributs du produit: Reacts with the 97-115 kDa cell surface glycoprotein, E-selectin, also known as endothelial-leukocyte adhesion molecule-1 (ELAM-1). E-selectin is thought to be involved in the initial interaction of neutrophils with inflammed endothelium. CD62E is expressed on cytokine-stimulated endothelium, but in minimal amounts on unstimulated endothelium. The adhesion between endothelial E-selectin molecules and a carbohydrate ligand on neutrophils is inhibited by the mAb 68-5H11. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of TNFa-stimulated HUVEC cells analyzed on a FACScan

BD Pharmingen™ Biotin Mouse Anti-Human CD62E - Biotin - Clone 68-5H11 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: 68

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Références pour anticorps anti-Selectin E/CD62e (Biotin) (ABIN2689357)

Phillips, Nudelman, Gaeta, Perez, Singhal, Hakomori, Paulson: "ELAM-1 mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex." dans: Science (New York, N.Y.), Vol. 250, Issue 4984, pp. 1130-2, (1991) (PubMed).

Bevilacqua, Stengelin, Gimbrone, Seed: "Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins." dans: Science (New York, N.Y.), Vol. 243, Issue 4895, pp. 1160-5, (1989) (PubMed).

Guesdon, Ternynck, Avrameas: "The use of avidin-biotin interaction in immunoenzymatic techniques." dans: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 27, Issue 8, pp. 1131-9, (1979) (PubMed).

Détails sur Selectin E/CD62e

Antigène: Selectin E/CD62e (SELE) (Selectin E (SELE))

Autre désignation: CD62E (SELE Produits)

Synonymes: anticorps SELE, anticorps CD62E, anticorps ELAM, anticorps ELAM1, anticorps ESEL, anticorps LECAM2, anticorps E-selectin, anticorps Elam, anticorps selectin E, anticorps selectin, endothelial cell, anticorps SELE, anticorps Sele

Sujet: Synonyms: E-Selectin

Pathways: Thromboxane A2 Receptor Signaling