CEACAM6 anticorps

N° du produit ABIN2689376

Détail du produit anti-CEACAM6 anticorps

Antigène: CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CEACAM6 est non-conjugé

Application: Flow Cytometry (FACS)

Marque: BD Pharmingen™

Attributs du produit: Reacts with two glycosylphosphatidylinositol-anchored glycoprotein present on granulocytes. Antibody B6.2 was studied as recognizing CD66c in the VI Human Leukocyte Differentiation Antigen workshop. CD66 antigens also known as the carcinoembryonic antigen (CEA) family of molecules, are closely related to the immunoglobulin super family of glycoproteins. Studies on CD66 Molecules suggest a potential adhesion function in vivo. These molecules exhibit both homophilic and heterophilic adhesion. CEA family members may be involved in transmembrane signalling and activation of neutrophils. This clone has been found to be N-terminal domain reactive, reacted preferentially with the native protein and were conformationally dependent. Profile of peripheral blood granulocytes analyzed by flow cytometry. Second step staining with Cat. No. 555988.

BD Pharmingen™ Purified Mouse Anti-Human CD66c - Purified - Clone B6.2/CD66 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: B6-2-CD66

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-CEACAM6 (ABIN2689376)

Watt, Teixeira, Zhou, Doyonnas, Zhang, Grunert, Blumberg, Kuroki, Skubitz, Bates: "Homophilic adhesion of human CEACAM1 involves N-terminal domain interactions: structural analysis of the binding site." dans: Blood, Vol. 98, Issue 5, pp. 1469-79, (2001) (PubMed).

Skubitz, Campbell, Ahmed, Skubitz: "CD66 family members are associated with tyrosine kinase activity in human neutrophils." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 11, pp. 5382-90, (1995) (PubMed).

Kuroki, Arakawa, Matsuo, Oikawa, Misumi, Nakazato, Matsuoka: "Molecular cloning of nonspecific cross-reacting antigens in human granulocytes." dans: The Journal of biological chemistry, Vol. 266, Issue 18, pp. 11810-7, (1991) (PubMed).

Thompson, Grunert, Zimmermann: "Carcinoembryonic antigen gene family: molecular biology and clinical perspectives." dans: Journal of clinical laboratory analysis, Vol. 5, Issue 5, pp. 344-66, (1991) (PubMed).

Szpak, Johnston, Lottich, Kufe, Thor, Schlom: "Patterns of reactivity of four novel monoclonal antibodies (B72.3, DF3, B1.1 and B6.2) with cells in human malignant and benign effusions." dans: Acta cytologica, Vol. 28, Issue 4, pp. 356-67, (1984) (PubMed).

Détails sur CEACAM6

Antigène: CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))

Autre désignation: CD66c (CEACAM6 Produits)

Synonymes: anticorps CD66c, anticorps CEAL, anticorps NCA, anticorps carcinoembryonic antigen-related cell adhesion molecule 6, anticorps carcinoembryonic antigen related cell adhesion molecule 6, anticorps Ceacam6, anticorps CEACAM6

Sujet: Synonyms: CEA, carcinoembryonic antigen