IL-1 beta anticorps

N° du produit ABIN2689747

Cité dans 2 publications. Cet anticorps anti-IL-1 beta Monoclonal Hamster arménien (Clone B122) (ABIN2689747) détecte spécifiquement IL-1 beta dans WB, IP, ELISA et Neut. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour IL-1 beta anticorps (ABIN2689747)

Antigène: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Reactivité: Souris

Hôte: Hamster arménien

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-1 beta est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), ELISA, Neutralization (Neut)

Clone: B122

Détail du produit anti-IL-1 beta anticorps

Attributs du produit: The B122 antibody recognizes the precursor and mature secreted forms of the mouse IL-1β protein. B122 neutralizes the biological activity of mouse IL-1β, but not the biological activities of mouse IL-1α nor human IL-1β. B122 does not recognize mouse IL-2, IL-4, IL-6, IL-10, TNF or IFN-γ. This antibody also recognizes rat IL-1β. The immunogen used to generate the B122 hybridoma was a purified, mature form of the mouse IL-1β protein.

BD Pharmingen™ Purified Hamster Anti-Mouse IL-1β - Purified - Clone B122 - Isotype Armenian Hamster IgG, λ1 - Reactivity Ms - 0.5 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Mouse IL-1beta

Isotype: IgG lambda

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-IL-1 beta (ABIN2689747)

Miller, Krasney, Gauvin, Holbrook, Koonz, Abruzzese, Miller, Pagani, Dolle, Ator: "Inhibition of mature IL-1 beta production in murine macrophages and a murine model of inflammation by WIN 67694, an inhibitor of IL-1 beta converting enzyme." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 3, pp. 1331-8, (1995) (PubMed).

Hogquist, Nett, Sheehan, Pendleton, Schreiber, Chaplin: "Generation of monoclonal antibodies to murine IL-1 beta and demonstration of IL-1 in vivo." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 146, Issue 5, pp. 1534-40, (1991) (PubMed).

Détails sur IL-1 beta

Antigène: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Autre désignation: IL-1beta

Pathways: Signalisation NF-kappaB, Interferon-gamma Pathway, Signalisation TLR, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome