ATP6V1B1 anticorps

N° du produit ABIN2716451

Détail du produit anti-ATP6V1B1 anticorps

Antigène: ATP6V1B1 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B1 (ATP6V1B1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ATP6V1B1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Attributs du produit: Homo sapiens ATPase, H+ transporting, lysosomal 56/58 kDa, V1 subunit B1 (ATP6V1B1)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human ATP6V1B1 (NP_001683) produced in HEK293T cell.

Clone: 2D2

Isotype: IgG2b

Information d'application

Indications d'application: WB 1:500~2000, IF 1:100, FLOW 1:100

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur ATP6V1B1

Antigène: ATP6V1B1 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B1 (ATP6V1B1))

Autre désignation: ATP6V1B1 (ATP6V1B1 Produits)

Synonymes: anticorps ATP6B1, anticorps RTA1B, anticorps VATB, anticorps VMA2, anticorps VPP3, anticorps AW208839, anticorps Atp6b1, anticorps D630003L15, anticorps D630030L16Rik, anticorps D630039P21Rik, anticorps Vpp-3, anticorps Vpp3, anticorps ATPase H+ transporting V1 subunit B1, anticorps ATPase, H+ transporting, lysosomal V1 subunit B1, anticorps ATP6V1B1, anticorps Atp6v1b1

Sujet: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness.

Poids moléculaire: 56.7 kDa

ID gène: 525

NCBI Accession: NM_001692

HGNC: 525

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis, Proton Transport