POU2F1 anticorps

N° du produit ABIN271753

Détail du produit anti-POU2F1 anticorps

Antigène: POU2F1 (POU Domain, Class 2, Transcription Factor 1 (POU2F1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POU2F1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of OCT1/OTF1 protein. (region surrounding Leu68)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store Store the antibody undiluted at 2-8 °C.

Détails sur POU2F1

Antigène: POU2F1 (POU Domain, Class 2, Transcription Factor 1 (POU2F1))

Autre désignation: POU2F1 / OCT1 (POU2F1 Produits)

Synonymes: anticorps OCT1, anticorps OTF1, anticorps oct-1B, anticorps POU2F1, anticorps 2810482H01Rik, anticorps NF-A1, anticorps Oct-1, anticorps Oct1, anticorps Otf-1, anticorps Otf1, anticorps chOCT-1, anticorps oct-1, anticorps oct1, anticorps pou2f1r, anticorps fc07d06, anticorps wu:fc07d06, anticorps zgc:158360, anticorps POU class 2 homeobox 1, anticorps POU domain, class 2, transcription factor 1, anticorps POU class 2 homeobox 1 S homeolog, anticorps POU class 2 homeobox 1b, anticorps POU2F1, anticorps Pou2f1, anticorps pou2f1.S, anticorps pou2f1b

Sujet: Organic cation transporters (OCT) are expressed in the plasma membrane of epithelial cells from a wide range of tissues, where they function in the elimination of endogenous amines, cationic drugs and other xenobiotics. The structure of OCTs consists of a 12-transmembrane-domain structure and a large extracellular hydrophilic loop. In humans, OCT1 is primarily expressed in the liver while OCT2 is expressed in the kidney. OCT3 is expressed in the placenta, skeletal muscle, prostate, aorta and liver. OCT3, also known as extraneuronal monoamine transporter, is widely expressed in different regions of the brain including the hippocampus, cerebellum and cerebral cortex. OCT3 mediates the uptake of several neuroactive agents, including dopamine, and may play an important role in the disposition of neurotransmitters and cationic neurotoxins in the brain. The genes encoding human OCT1-3 map to a conserved cluster at chromosome 6q26-q27.Synonyms: NF-A1, OTF1, Oct-1, Octamer-binding protein 1, Octamer-binding transcription factor 1, Otf-1, POU domain class 2 transcription factor 1

Poids moléculaire: approx. 89 kDa

ID gène: 5451

NCBI Accession: NP_001185712

UniProt: P14859