GAD anticorps
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- Antigène Voir toutes GAD (GAD1) Anticorps
- GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GAD est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody detects endogenous levels of GAD1/2 protein. (region surrounding Asp572)
- Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- Pureté
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product GAD1 Anticorps primaire
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- Indications d'application
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ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- DO NOT FREEZE!
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- Antigène
- GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
- Autre désignation
- GAD1 / GAD67 (GAD1 Produits)
- Synonymes
- anticorps CPSQ1, anticorps GAD, anticorps SCP, anticorps GAD-67, anticorps cpsq1, anticorps gad1, anticorps gad1-A, anticorps gad67, anticorps GAD67, anticorps GAD1, anticorps GLUTAMATE DECARBOXYLASE, anticorps GLUTAMATE DECARBOXYLASE 1, anticorps MKP11.30, anticorps MKP11_30, anticorps glutamate decarboxylase, anticorps EP10, anticorps GAD25, anticorps GAD44, anticorps Gad-1, anticorps Gad67, anticorps glutamate decarboxylase 1, anticorps glutamate decarboxylase 1 L homeolog, anticorps glutamate decarboxylase, anticorps glutamate decarboxylase 1b, anticorps GAD1, anticorps gad1.1.L, anticorps GAD, anticorps Gad1, anticorps gad1b
- Sujet
- This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.Synonyms: 67 kDa glutamic acid decarboxylase, GAD-67, Glutamate decarboxylase 1, Glutamate decarboxylase 67 kDa isoform
- Poids moléculaire
- approx. 65, 67 kDa
- ID gène
- 2571
- NCBI Accession
- NP_000808
- UniProt
- Q99259
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